Non Small Cell Lung Cancer Stage 4 Clinical Trials

For expansion cohorts patient s tumor must also harbor a kras mutation detected in a clia certified laboratory have histologically or cytologically confirmed non small cell lung cancer.

Non small cell lung cancer stage 4 clinical trials.

As part of our commitment to providing innovative treatment options to our patients the doctors at ctca may recommend that stage iv lung cancer patients enroll in carefully selected clinical trials. M7824 in combination with chemotherapy in stage iv non small cell lung cancer nsclc the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Stage 4 non small cell lung cancer nsclc also called metastatic lung cancer is the most advanced stage of this disease and refers to any size and type of nsclc adenocarinoma squamous cell carcinoma large cell carcinoma that has spread from one lung to the other lung to another region of the body or to the fluid around the lung or heart. Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

There is cancer in both lungs. The study is a prospective randomized controlled phase iii trial aimed to test the efficacy and safety of ttfields using the novottf 100l system concurrent with standard therapies for stage 4 nsclc patients following progression while on or after platinum based treatment the device is an experimental portable battery operated device for chronic administration of alternating electric fields termed ttfields or ttf to the region of the malignant tumor by means of surface insulated. A study of nivolumab plus ipilimumab in combination with chemotherapy vs chemotherapy alone as first line therapy in stage iv non small cell lung cancer nsclc the purpose of this research study is to see if nivolumab and ipilimumab in combination with chemotherapy is better at improving survival when compared to standard chemotherapy treatment. The cancer is in the covering of the lung the pleura or the covering of the heart pericardium.

This randomized phase ii trial studies how well giving erlotinib tarceva with or without bevacizumab avastin works in treating patients with stage iv non small cell lung cancer nsclc with epidermal growth factor receptor egfr mutations. This phase ii lung map treatment trial studies how well selpercatinib works in treating patients with ret fusion positive non small cell lung cancer that is stage iv or has come back recurrent. Stage iv or metastatic recurrent non small cell lung cancer. Search our clinical trials database for all cancer trials and studies recruiting in the uk.

Non small cell lung cancer. Listing a study does not mean it has been evaluated by the u s. In stage 4 the cancer has spread metastasized to both lungs the area around the lungs or distant organs. Selpercatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Clinical trials are a key testing ground for determining the effectiveness and safety of new treatments for many types and stages of cancer including stage iv lung cancer. It is also called advanced lung cancer.